Paper of the Month - Archive
December 2010 (PDF - 810KB)
Alveolar macrophages stimulate enhanced cytokine production by pulmonary CD4+ T-lymphocytes in an exacerbation of murine chronic asthma
Authors: Cristan Herbert, Melissa M. Scott, Kim H. Scruton, Rylie P. Keogh, Kristy C. Yuan, Kenneth Hsu, Jessica S. Siegle, Nicodemus Tedla, Paul S. Foster, and Rakesh K. Kumar
November 2010 (PDF – 175KB)
Chronic high-fat diet in fathers programs b-cell dysfunction in female rat offspring, Nature 467: 963-967.
Authors: Sheau-Fang Ng, Ruby Lin, D. Ross Laybutt, Romain Barres, Julie Owens and Margaret Morris
October 2010 (PDF – 760KB)
Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion, (PNAS) Proceedings of the National Academy of Sciences USA, 107 (40): 17397–402.
Authors: Phoebe Phillips, Lu Yang, Arthur Shulkes, Alain Vonlaufen, Anne Poljak, Sonia Bustamante, Alessandra Warren, Zhihong Xu, Michael Guilhaus, Romano Pirola, Minoti Apte, and Jeremy Wilson
September 2010 (PDF – 434KB)
Surgical anatomy of the uterosacral ligament, Int Urogynecol J Pelvic Floor Dysfunct. Sept, 21 (9): 1123-8.
Authors: D Vu, BT Haylen, K Tse, and A Farnsworth
August 2010 (PDF – 383KB)
Soluble LILRA3, a Potential Natural Anti-inflammatory Protein, Is Increased in Patients with Rheumatoid Arthritis and Is Tightly Regulated by Interleukin 10, Tumor Necrosis Factor-α, and Interferon-γ, The Journal of Rheumatology, 37: 8; doi:10.3899/jrheum.091119.
Authors: Hongyan An, Vasudha Chandra, Barbara Piraino, Luis Borges, Carolyn Geczy, H. Patrick Mcneil, Katherine Bryant and Nicodemus Tedla
July 2010 (PDF – 456KB)
Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus, Psychoneuroendocrinology doi:10.1016/ j.psyneuen.2010.05.012.
Authors: Jayanthi Maniam and Margaret J. Morris
June 2010 (PDF – 648KB)
External divalent cations increase anion–cation permeability ratio in glycine receptor channels, Pflügers Archiv - European Journal of Physiology, 460 (1): 131-152.
Authors: Silas Sugiharto, Jane E. Carland, Trevor M. Lewis, Andrew J. Moorhouse and Peter H. Barry
May 2010 (PDF – 1.85MB)
S-glutathionylation regulates inflammatory activities of S100A9, Journal of Biological Chemistry, 285 (19): 14377-88.
Authors: S.Y. Lim, M.J. Raftery, J. Goyette, C.L. Geczy
April 2010 (PDF – 507KB)
Geological setting and age of Australopithecus sediba from southern Africa, Science, 328: 205-209.
Authors: P.H.D.M. Dirks, J.N. Kibii, B.F. Kuhn, C. Steininger, S.E. Churchill, J.D. Kramers, R. Pickering, D.L. Farber, S-A. Mériaux, A.I.R. Herries, G.C.P. King, L.R. Berger
March 2010 (PDF – 738KB)
New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2, European Journal of Cell Biology, 89 (7): 489-498.
Authors: Thomas Fath, Yee-Ka Agnes Chan, Bernadette Vrhovski, Hamish Clarke, Nikki Curthoys, Jeff Hook, Frances Lemckert, Galina Schevzov, Patrick Tam, Catherine Watson, Poh-Lynn Khoo and Peter Gunning
February 2010 (PDF – 634KB)
The Evolutionary Dynamics of a Rapidly Mutating Virus within and between Hosts: The Case of Hepatitis C Virus, PLoS Computational Biology, 5 (11): e1000565. doi:10.1371/journal.pcbi.1000565.
Authors: Fabio Luciani and Samuel Alizon
January 2010 (PDF – 1.08MB)
Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice, Respiratory Research, 11:14 doi:10.1186/1465-9921-11-14
Authors: Jessica Siegle, Nicole Hansbro, Cristan Herbert, Helene Rosenberg, Joseph Domachowske, Kelly Asquith, Paul Foster and Rakesh Kumar
December 2009 (PDF – 1.78MB)
Leukocyte Ig-like receptor B4 (LILRB4) is a potent inhibitor of Fc_RI-mediated monocyte activation via dephosphorylation of multiple kinases, Journal of Biological Chemistry, 284 (50): 34839-48.
Authors: Hao Kim Lu, Carles Rentero, Mark Raftery, Luis Borges, Katherine Bryant and Nicodemus Tedla
November 2009 (PDF – 2.95MB)
Stem Cell Activity in the Developing Human Cornea, Stem Cells, 27 (11): 2781–2792.
Authors: Sarah B. Davies, Jeanie Chui, Michelle C. Madigan, Jan M. Provis, Denis Wakefield, Nick Di Girolamo
October 2009 (PDF – 443KB)
Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathy, Brain, 132 (10): 2712-2723.
Authors: Susanna B. Park, Cindy S.-Y. Lin, Arun V. Krishnan, David Goldstein, Michael L. Friedlander and Matthew C. Kiernan
September 2009 (PDF – 2.2MB)
Rapid somatic expansion causes the brain to lag behind: The case of the brain and behavior of New Zealand’s Haast’s eagle, Journal of Vertebrate Paleontology, 29 (3) 637-649.
Authors: R P Scofield and K W S Ashwell
August 2009 (PDF – 449KB)
Fire as an Engineering Tool of Early Modern Humans, Science, Vol. 325: 859
Authors: Kyle S Brown, Curtis W Marean, Andy I R Herries, Zenobia Jacobs, Chantal Triboo, David Braun, David L Roberts, Michael C Meyer, Jocelyn Bernatchez
July 2009 (PDF – 3.28MB)
Pleiotropic Roles of S100A12 in Coronary Atherosclerotic Plaque Formation and Rupture, The Journal of Immunology, Vol. 183: 593–603.
Authors: J Goyette, W X Yan, E Yamen, Y M Chung, S Y Lim, K Hsu, F Rahimi, N D Girolamo, C Song, W Jessup, M Kockx, Y V Bobryshev, S B Freedman and C L Geczy
June 2009 (PDF – 535KB)
Mechanism for Quinolinic Acid Cytotoxicity in Human Astrocytes and Neurons, Journal Neurotoxicity Research, doi: 10.1007/s12640-009-9051-z.
Authors: N Braidy, R Grant, S Adams, B J Brew and G J Guillemin
May 2009 (PDF – 480KB)
Characterization of Rat Forepaw Function in Two Models of Cervical Dorsal Root Injury, The Journal of Neurotrauma, Vol. 26: 17–29.
Authors: A Wu, J L Lauschke, R Morris and P M E Waite
April 2009 (PDF – 262KB)
Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid, Journal of Neurochemistry, Vol. 108, 1220-1225.
Authors: S Coggan, G Smythe, A Bilgin and R Grant
March 2009 (PDF – 3.20MB)
Alternate mRNA Splicing in Multiple Human Tryptase Genes is Predicted to Regulate Tetramer Formation, Journal of Biological Chemistry (2008), Vol. 283 (49): 34178-34187.
Authors: N E Jackson, H-W Wang, K J Bryant, H P McNeil, A Husain, K Liu, N Tedla, P S Thomas, G C King, A Hettiaratchi, J Cairns and J E Hunt
February 2009 (PDF- 701KB)
IL-10-Dependent S100A8 Gene Induction in Monocytes/Macrophages by Double-Stranded RNA1, The Journal of Immunology, (2009) 182: 2258–2268.
Authors: Y Endoh, Y M Chung, I A Clark, C L Geczy and K Hsu
January 2009 (PDF- 556KB)
Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in _1 Glycine Receptor Channels, Journal of Biological Chemistry, (2009) Vol 284, no 4: 2023–2030
Authors: J E Carland, M A Cooper, S Sugiharto, H-J Jeong, T M Lewis, P H Barry, J A Peters, J J Lambert and A J Moorhouse
December 2008 (PDF- 655KB)
Correlations between hand preference and cortical thickness in the secondary somatosensory (SII) cortex of the common marmoset, callithrix jacchus. Behavioral Neuroscience, Vol 122, no 6: 1343–51
Authors: C A Gorrie, P M Waite and L J Rogers
November 2008 (PDF- 486KB)
Anion-Cation Permeability Correlates with Hydrated Counter-ion Size in Glycine Receptor Channels. Biophysical Journal. Vol 95: 4698-4715
Authors: S Sugiharto, T M Lewis, A J Moorhouse, P R Schofield and P H Barry
October 2008 (PDF- 419KB)
S-Nitrosylated S100A8: Novel Anti-Inflammatory Properties. The Journal of Immunology, 181: 5627–5636
Authors: S Y Lim, M Raftery, H C, K Hsu, W X Yan, H-L Hseih, R Watts, D Richardson, S Thomas, M Perry and C Geczy
September 2008 (PDF- 79KB)
Mechanisms of neonatal increase in glomerular filtration rate. Am J Physiol Regul Integr Comp Physiol. 295: R916–R921, doi:10.1152/ajpregu.00823.2007.
Authors: A Turner, R Brown, M Carlstrom, K Gibson and E G Persson
August 2008 (PDF- 324KB)
Nerve function and dysfunction in acute intermittent porphyria. Brain, doi: 10.1093/brain/awn152.
Authors: C S Lin, A V Krishnan, M J Lee, AS Zagami, H L You, C C Yang, H Bostock and M C Kiernan.
July 2008 (PDF- 377KB)
Maternal and postnatal over nutrition differentially impact appetite regulators and fuel metabolism. Endocrinology, doi:10.1210/en.2008-0582
Authors: H Chen, D Simar, K Lambert, J Mercier and M J Morris
May 2008 (PDF- 920KB)
A novel role for adiponectin in regulating the immune responses in chronic HCV infection. Hepatology, Vol 48, no 2: 374-384
Authors: C Palmer, T Hampartzoumian, A Lloyd and A Zekry
April 2008 (PDF- 1.0MB)
Cardiovascular and behavioural responses to conditioned fear after medullary raphe neuronal blockade. Neuroscience, doi:10.1016/j.neuroscience.2008.03.033.
Authors: D M L Vianna, C Allen and P Carrive
March 2008 (PDF- 664KB)
Suppression of cytokine expression by roflumilast and dexamethasone in a model of chronic asthma. Clinical and Experimental Allergy, doi:10.1111/j.1365-2222.2008.02950.x
Authors: C Herbert, A. Hettiaratchi, D C Webb, P S Thomas, P S Foster and R K Kumar
February 2008 (PDF- 352KB)
Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts?. British Journal of Pharmacology; doi:10.1038/bjp.2008.29
Authors: P Sadananda, R Chess-Williams and E Burcher
January 2008 (PDF- 129KB)
The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women. International Journal of Obesity, doi:10.1038/sj.ijo.0803781.
Authors: E G Trapp, D J Chisholm, J Freund and S H Boutcher
December 2007 (PDF - 398KB)
Characterization of the Kynurenine Pathway in Human Neurons. The Journal of Neuroscience, November 21, 2007 27(47):12884 –12892
Authors: Gilles J. Guillemin, Karen M. Cullen, Chai K. Lim, George A. Smythe, Brett Garner, Vimal Kapoor, Osamu Takikawa, and Bruce J. Brew
November 2007 (PDF – 108KB)
Polymorphisms in Toll-like receptors-2 and -4 are not associated with disease manifestations in acute Q fever. Genes and Immunity (2007), 1–4
Authors: B Everett, B Cameron, H Li, U Vollmer-Conna, T Davenport, I Hickie, D Wakefield, S Vernon, WC Reeves and AR Lloyd
October 2007 (PDF-641 KB)
The Role of Substance P in the Pathogenesis of Pterygia published in Investigative Ophthalmology and Visual Science, 48 (10): 4482-4489
Authors: J Chui, N Di Girolamo, M T Coroneo, and D Wakefield
September 2007 (PDF- 4273 KB)
Bacterial endotoxin - a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model published in Gastroenterology, 133 (4): 1293-1303
Authors: A Vonlaufen, Z Xu, B Daniel, R K Kumar, R Pirola, J Wilson and M V Apte
August 2007 (PDF- 618 KB)
Conformational activation of CD11b without shedding of L-selectin on circulating human neutrophils published in Journal of Leukocyte Biology, 82: 1115-1125
Authors: Y Orr, J M Taylor, S Cartland, P G Bannon, C Geczy, and L Kritharides
July 2007 (PDF- 266 KB)
Branched fibers in dystrophic mdx muscle are associated with a loss of force following lengthening contractions published in American Journal of Physiology-Cell Physiol. 293: 985-992
Authors: S Chan, S I Head and J W Morley
June 2007 (PDF – 632 KB)
Structure of the d(CGCGAATTCGCG)2 Complex of the Minor Groove Binding Alkylating Agent Alkamin Studied by Mass Spectrometry published in Molecular Pharmacology, 71: 1165–1178
Authors: A M S Abdul Majid, G Smythe, W A Denny, and L P G Wakelin
May 2007 (PDF – 356 KB)
Gene Expression Correlates of Postinfective Fatigue Syndrome after Infectious Mononucleosis published in Journal of Infectious Diseases, 196:56-66
Authors: B Cameron, S Galbraith, Y Zhang, T Davenport, U Vollmer-Conna, D Wakefield, I Hickie, W Dunsmuir, T Whistler, S Vernon, W C Reeves, and A R Lloyd
April 2007 (PDF- 154 KB)
Endothelium-independent constriction of isolated, pressurized arterioles by N 
-nitro-L-arginine methyl ester (L-NAME) published in British Journal of Pharmacology, 151: 602–609
Authors: T V Murphy, N Kotecha and M A Hill
March 2007 (PDF- 280 KB)
The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer published in British Journal of Cancer 96, 783-792
Authors: A Hettiaratchi, N Hawkins, G McKenzie, R Ward, J Hunt, D Wakefield and N Di Girolamo
February 2007 (PDF- 208 KB)
Ultraviolet B irradiation selectively increases the production of interleukin-8 in human cord blood-derived mast cells published in Clinical and Experimental Immunology, 148: 161-167.
Authors: I Endoh, N Di Girolamo, T Hampartzoumian, B Cameron, C L Geczy and N Tedla
January 2007 (PDF- 463 KB)
Down-regulation of Leukocyte Immunoglobulin-like Receptor Expression in the Synovium of Rheumatoid Arthritis Patients after Treatment with Disease-Modifying Antirheumatic Drugs published in Journal Rheumatology, 46: 742–751
Authors: O A Huynh, T Hampartzoumian, J P Arm, J E. Hunt, L Borges, Ml Ahern, M Smith, C L Geczy, H P McNeil and N Tedla
March 2006 (PDF - 521KB)
Vibrotactile frequency discrimination in human hairy skin published in The Journal of Neurophysiology 95:1442-1450.
Authors: D Mahns, N M Perkins, V Sahai, L Robinson & M J Rowe
Processing of vibrotactile Inputs from hairy skin by neurons of the dorsal column nuclei in the cat published in The Journal of Neurophysiology 95:1451-1464.
Authors: V Sahai, D A Mahns, L Robinson, N M Perkins, G T Coleman & M J Rowe
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Vibrotactile coding capacities of spinocervical tract neurons in the cat published in The Journal of Neurophysiology 95:1465-1477.
Authors: V Sahai, D A Mahns, N M Perkins, L Robinson & M J Rowe
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February 2006 (PDF - 421KB)
Whisker Maps in Marsupials: Nerve Lesions and Critical Periods published in The Anatomical Record Part A (2006) 288A:174-181
Authors: Phil M E Waite, Catherine A Gorrie, Nimali P Herath and Lauren R Marotte
January 2006 (PDF - 2.8MB)
Description, new reconstruction, comparative anatomy, and classification of the Sterkfontein Stw 53 cranium, with discussions about the taxonomy of other southern African early Homo remains published in Journal of Human Evolution 50: 36-77
Authors: Darren Curnoe and Phillip V Tobias
December 2005 (PDF - 528KB)
Bioceramics compositionmodulate resorption of human osteoclasts published in Journal of Materials Science: Materials in Medicine 16(12):1199-1205
Authors: Y Ramaswamy, D R Haynes, G Berger, R Gildenhaar, H Lucas, C Holding, H Zreiqat
October 2005 (PDF - 659KB)
Mechanism of Selectivity of an Angiogenesis Inhibitor From Screening a Genome-Wide Set of Saccharomyces cerevisiae Deletion Strains published in J National Cancer Inst 97: 1539-1547
Authors: Pierre J Dilda, Anthony S Don, Kara M Tanabe, Vincent J Higgins, John D Allen, Ian W Dawes, Philip J Hogg
September 2005 (PDF - 628KB)
Inducible platelet-derived growth factor D-chain expression by angiotensin II and hydrogen peroxide involves transcriptional regulation by Ets-1
and Sp1 published in Blood. Sep 27; [Epub ahead of print]
Authors: Mary Yanxia Liu, Melanie Eyries, Chunyan Zhang, Fernando S Santiago and Levon M Khachigian
August 2005 (PDF - 311KB)
IL-15 induces mast cell migration via a pertussis toxin-sensitive receptor published in Eur J Immunol 35: 2376-85
Authors: Nicole E Jackson, Hong-Wei Wang, Nicodemus Tedla, H Patrick McNeil, Carolyn L Geczy, Andrew Collins, Michael C Grimm, Taline Hampartzoumian and John E Hunt
July 2005 (PDF - 225KB)
The amplitude of Mmax in human wrist flexors varies during different muscle contractions despite constant posture published in J. Neurosci Methods online
Authors: Michael Lee, Timothy J Carroll
June 2005 (PDF - 725KB)
FGF-2, IL-1¾ and TGF-¾ regulate fibroblast expression of S100A8 published in FEBS, 2005, 272(11):2811-2827
Authors: Farid Rahimi, Kenneth Hsu, Yasumi Endoh and Carolyn L Geczy
May 2005 (PDF - 1.5MB)
Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apoA-I pathway. 1-Phenyl-2-Decanoylamino-3-Morpholino-1-Propanol is a novel cholesterol efflux accelerator. J Biol Chem. 2005 May 11; [Epub ahead of print]
Authors: Elias N Glaros, Woojin Scott Kim, Carmel M Quinn, Jenny Wong, Ingrid Gelissen, Wendy Jessup and Brett Garner
April 2005 (PDF - 296KB)
Probucol protects against hypochlorite-induced endothelial dysfunction published in Journal of Biological Chemistry, 280, 15612-18
Authors: Paul K Witting, Ben J Wu, Mark Raftery, Peter Southwell-Keely and Roland Stocker
March 2005 (PDF - 86KB)
Simple formula for the surface area of the body and a simple model for anthropometry published in Clinical Anatomy 8:126-130
Authors: Bruce Reading and Brian Freeman
February 2005 (PDF - 128KB)
Dolichol is the major lipid component of human substantia nigra neuromelanin published in Journal of Neurochemistry, 92, 990-995
Authors: Heidi Fedorow, Russell Pickford, James M Hook, Kay L Double, Glenda M Halliday, Manfred Gerlach, Peter Riederer and Brett Garner
January 2005 (PDF - 2.5 MB)
Cyto- and Chemoarchitecture of the Cerebral Cortex of an Echidna (Tachyglossus aculeatus). II. Laminar Organization and Synaptic Density published in Journal of Comparative Neurolog, (January 31, 2005)
Authors: Maria Hassiotis, George Paxinos and Ken WS Ashwell
December 2004 (PDF - 754 KB)
Effects of cortisol on cardiac myocytes and on expression of cardiac genes in fetal sheep published in American Journal of Physiology – Regulatory, Integrative and Comparative Physiology (December 2, 2004)
Authors: Eugenie R Lumbers, Amanda C Boyce, Georgina Joulianos, Vasumathy Kumarasamy, E Barner, JL Segar, and JH Burrell
November 2004 (PDF - 119 KB)
Expression and Regulation of Sterol 27-Hydroxylase (CYP27A1) in Human Macrophages: A role for RXR and PPAR-gamma ligands published on line in the Biochemical Journal
Authors: Carmel M Quinn, Wendy Jessup, Jenny Wong, Leonard Kritharides, Andrew J Brown
October 2004 (PDF - 2.2 MB)
Predicting the Impact of a Nonsterilizing Vaccine against Human Immunodeficiency Virus published in J. Virology 78, 11340-351
Authors: Miles P Davenport, Ruy M Ribeiro, Dennis L Chao, Alan S Perelson
September 2004 (PDF - 0.1 MB)
Probucol Protects Against Smooth Muscle Cell Proliferation by Upregulating Heme Oxygenase-1 published in Circulation 110 (13), 1861-1866
Authors: Yi-Mo Deng, Ben J Wu, Paul K Witting, Roland Stocker
August 2004 (PDF - 0.5 MB)
Ets-1 Stimulates Platelet-Derived Growth Factor A-Chain Gene Transcription and Vascular Smooth Muscle Cell Growth via Cooperative Interactions With Sp1 published in Circulation Research 2004 ;95:479
Authors: Fernando S Santiago, Levon M Khachigian
July 2004 (PDF - 108KB)
Long-term depression is reduced in cerebellar Purkinje cells of dystrophin-deficient mdx mice published in Brain Research 1019 (2004) 289-292
Authors: Jennifer L Anderson, Stewart I Head, John W Morley